- Global stocks diverge on renewed US inflation fears
- France coach Deschamps to step down after 2026 World Cup
- French magazine run by autistic journalists hits newsstands
- US, Canadian and Australian travellers now face UK entry fee
- France urges European Commission to be firm against Musk interference
- Wildfire sparks panicked evacuations in Los Angeles suburbs
- Nobel winner Ressa tells AFP 'dangerous times' ahead after Meta ends US fact-checking
- Indonesia upholds iPhone 16 sales ban after Apple offers $1 bn investment
- Dutch great Kluivert named Indonesia coach in hunt for World Cup spot
- UK's Catherine turns 43 hoping for better year
- France coach Deschamps says will leave after 2026 World Cup
- South Syria fighters reluctant to give up weapons: spokesman
- Dutch great Kluivert named coach of Indonesia
- New Zealand crush Sri Lanka by 113 runs in 2nd ODI to win series
- West Ham cancel Lopetegui press conference as sacking rumours swirl
- Questions remain over South African involvement in Champions Cup
- OpenAI chief Sam Altman denies sister's sexual abuse accusations
- Hundreds rally for South Korea's Yoon as new arrest bid beckons
- Bangladesh orders banks to assist UK minister graft probe
- Germans turn to balcony solar panels to save money
- Theekshana hat-trick restricts NZ to 255-9 in 2nd Sri Lanka ODI
- Young's buzzer-beater lifts Hawks, Celtics down Nuggets
- Grief and nostalgia in India's 'Jimmy Carter village'
- Venezuela's 'colectivos' ready to pounce as opposition plans protest
- Thai police hunt suspect over Cambodian politician shooting
- Venezuela on tenterhooks ahead of rival protests, Maduro swearing-in
- Devajit Saikia: lawyer, modest player and next India cricket chief
- S. Korea's impeached President Yoon holds out in capital 'fortress'
- Samsung warns fourth-quarter profit to miss forecasts
- China's viral wild boar hunters attract fame and concern
- Forgotten but not gone: Covid keeps killing, five years on
- Is the world ready for the next pandemic?
- Trump's provocative, often confusing, US foreign policy is back
- Rescuers search for survivors after quake in China's Tibet kills at least 126
- Brazil gears up for first climate conference in Amazon
- In Brazil, an Amazon reforestation project seeks to redeem carbon markets
- Djokovic with point to prove against younger rivals at Australian Open
- Asian markets mixed after Wall St hit by US inflation fears
- Mexicans offered $1,300 to hand in a machine gun
- Venezuela arrests two Americans, five other 'mercenaries'
- Iraqi archaeologists piece together ancient treasures ravaged by IS
- Big Tech rolls out the red carpet for Trump
- Kyrgios suffers new injury setback days before Australian Open
- Former US president Carter lies in state after somber Washington procession
- US company Firefly Aerospace to launch for Moon next week
- Don't eat your Christmas tree, warns Belgium food agency
- No proof fentanyl produced in Mexico, president says
- Multiple Viral Threats Amplify Call for Preparedness with Broad-Spectrum Antivirals
- Amphastar Pharmaceuticals to Present at the 43rd Annual J.P. Morgan Healthcare Conference
- Hemogenyx Pharmaceuticals PLC Announces Placing to raise £340,000
RBGPF | 100% | 59.31 | $ | |
BCC | -1.69% | 118.22 | $ | |
SCS | -2.14% | 11.2 | $ | |
GSK | 0.38% | 34.09 | $ | |
AZN | -0.3% | 66.64 | $ | |
NGG | -0.46% | 58.6 | $ | |
RIO | -0.33% | 58.19 | $ | |
BTI | -0.52% | 36.78 | $ | |
CMSC | -1.12% | 23.23 | $ | |
RYCEF | -0.42% | 7.17 | $ | |
RELX | 0.72% | 45.98 | $ | |
BCE | -0.34% | 23.86 | $ | |
CMSD | -1.15% | 23.46 | $ | |
VOD | -0.71% | 8.41 | $ | |
BP | 2.54% | 31.83 | $ | |
JRI | -1.88% | 12.22 | $ |
Adnexus Biotechnologies Inc. Unveils AI-Driven Malaria Cure with Trapicolast
Adnexus Biotechnologies Inc. is at the forefront of the battle against malaria by developing Trapicolast, an antimalarial medication created through the innovative Sutra™ AI platform. This advancement exemplifies the transformative potential of artificial intelligence in revolutionizing the drug discovery process.
Adnexus Biotechnologies Inc. proudly announces the launch of Trapicolast, a pioneering antimalarial drug developed through its innovative AI-powered Sutra™ platform. Integrating AI Platform discovered ADX1 and ADX2, this breakthrough medication targets dual mechanisms within the Plasmodium parasite, attacking both the apicoplast and vesicular trafficking pathways.
Figure 2 provides compelling evidence of how the Sutra™ AI Platform-driven discovery of ADX1 and ADX2 halt the DNA synthesis in malaria parasites, demonstrating Trapicolast's unique mechanism of action.
A New Era in Malaria Treatment
Traditional antimalarial treatments have primarily ignored the apicoplast, an organelle crucial for the parasite's survival. Trapicolast introduces a novel strategy by focusing on this overlooked target, providing a potent defence against the escalating challenge of drug resistance, especially against artemisinin-based therapies.
Revolutionizing Treatment with Dual-Target Mechanism
Trapicolast's unique dual-target approach disrupts the parasite's apicoplast DNA synthesis and vesicular trafficking, offering a robust and sustainable treatment option. This mechanism is particularly vital in areas where resistance to existing treatments is prevalent, offering new hope in regions like Sub-Saharan Africa and Southeast Asia.
The Power of AI in Drug Discovery
The creation of Trapicolast underscores the transformative impact of artificial intelligence in Drug Discovery. Leveraging the Sutra™ AI platform, Adnexus analyzed over 8 million molecular compounds, swiftly identifying Trapicolast. This approach exemplifies how AI can accelerate drug discovery, making it faster and more cost-effective. This discovery has been covered in a patent application.
Figure 1 demonstrates the Sutra™ AI Platform logo.
Figure 2 provides compelling evidence of how the Sutra™ AI Platform-driven discovery of ADX1 and ADX2 halt the DNA synthesis in malaria parasites, demonstrating Trapicolast's unique mechanism of action.
Key Features and Insights
Apicoplast Targeting: Trapicolast uniquely targets the apicoplast, a vital component of the Plasmodium parasite that previous treatments have largely neglected.
Dual-Target Mechanism: The combination of ADX1 and ADX2 in Trapicolast inhibits DNA synthesis and vesicular trafficking in the malaria parasite, making it resistant to developing resistance mechanisms.
Resistance Overcoming: With the rise of drug-resistant malaria strains, Trapicolast offers a promising new solution, especially in high-transmission areas like Sub-Saharan Africa and Southeast Asia.
Visionary Insights from Leadership
Dr. Kirsten Bischof, a distinguished member of Adnexus's Advisory Board and co-inventor, stated, "We have unlocked a new frontier in drug discovery by targeting the apicoplast to bypass resistance, potentially saving countless lives in regions heavily affected by malaria. Given the severe impact of malaria in high-transmission areas such as Africa and Asia, this innovation offers a more effective and sustainable management strategy, bringing hope for saving many lives. This is not just science; it is a beacon of hope."
Dr. Gaurav Chandra, CEO of Adnexus, exclaims, "The discovery of Trapicolast via our Sutra™ AI platform isn't just an advancement; it's a revolution. It showcases our commitment to pushing the boundaries of what's possible in medical science, promising a future where malaria might no longer claim lives. It also validates the potential of the Sutra™ AI platform in drug discovery." He further added." While meeting our milestones for our HIV assets is a priority, we will further advance this Malaria drug in collaboration with our partners in India with access to specific models and resistant strains."
Strategic Partnerships for Global Impact
Adnexus has solidified its commitment to innovation through a strategic partnership with 1606 Corp (OTC PINK:CBDW), aiming to expand its AI-driven healthcare solutions. This collaboration underscores Adnexus's dedication to advancing global health outcomes.
About Adnexus Biotechnologies Inc.
Adnexus Biotechnologies stands at the forefront of AI-enabled drug discovery, concentrating on treatments for infectious diseases like malaria and HIV. The company's proprietary Sutra™ AI platform is instrumental in:
Accelerating drug discovery processes
Identifying novel biomarkers for diseases
Advancing personalized medicine approaches
Market Insights
Global Malaria Treatment Market : This market is expected to grow to USD 2.93 billion by 2033, with the antimalarial drug sector growing at a CAGR of 4.26% from 2024 to 2030.
AI in Drug Discovery : The market for AI in drug discovery is expanding, highlighting AI's pivotal role in identifying new treatments for various diseases.
Forward-Looking Statements
This press release includes forward-looking statements that reflect Adnexus's goals and expectations regarding future developments, including Trapicolast's progress and AI's impact on drug discovery. These statements are based on current assumptions and are subject to risks and uncertainties that may cause actual results to differ.
Contact Us :
Dr. Gaurav Chandra
[email protected]
adnexusbiotech.com
cbdw.ai ( www.cbdw.ai )
SOURCE: Adnexus Biotechnologies Inc.
Related Images
B.Finley--AMWN